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Trends in utilization of glucose- and weight-lowering medications after tirzepatide approval in the United States: a population-based cohort study

These are not FDA-approved for weight loss and exist in a different regulatory category, but they represent options that some researchers explore as alternatives or adjuncts to tirzepatide

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Limited studies using hyperinsulinemic-euglycemic clamp techniquesthe gold standard for measuring insulin sensitivitysuggest that GLP-1 receptor agonists may improve peripheral insulin sensitivity, primarily through weight loss rather than direct cellular effects

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Delayed gastric emptying increases aspiration risk during sedated elective procedures